drugset / Trial / NCT05264025

Fexofenadine in Patients With Active Rheumatoid Arthritis

NCT05264025

Phase 1/2 Recruiting 80 enrolled October 6 University
RandomizedParallel-groupTriple-blindTreatment

Summary

Rheumatoid arthritis (RA) is an inflammatory autoimmune polyarthritis affecting ∼1% of the world population, resulting in the loss of joint function and progressive structural damage in affected joints. Fexofenadine has been widely used to treat various allergic diseases, like allergic rhinitis, conjunctivitis and chronic idiopathic urticaria. the molecular mechanisms underlying fexofenadine mediated inhibition of TNF-α signalling

Timeline

Start
2022-06-01
Primary completion
2025-12
Completion
2026-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fexofenadine Unknown

Indications