drugset / Trial / NCT05264493
Bioavailability Study of Naloxone 5 Milligrams (mg) Intramuscular (IM) Autoinjector
RandomizedCrossoverOpen-labelBasic science
Summary
To compare the plasma concentration (bioavailability) and safety of a single naloxone 5 mg autoinjector intramuscular (IM) injection to a single 2 mg IM injection (an approved safe dose) and to a single 2 mg bolus intravenous (IV) injection (an approved safe dose)
Timeline
- Start
- 2020-10-06
- Primary completion
- 2021-01-08
- Completion
- 2021-01-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naloxone | Small molecule | 2 mg | Intramuscular |
| Subject | Naloxone | Small molecule | 5 mg | Intramuscular |
Indications
No indication recorded.