The Effects of Oxytocin Treatment on Social Touch

Completed 180 enrolled University of Electronic Science and Technology of China

RandomizedParallel-groupTriple-blindBasic science

Summary

The main aim of the study is to investigate the modulatory effects of oxytocin (24IU) administration on the affective processing of touch manipulated differently in gentle caress-like stroke vs. social massage with a moderate pressure.

Timeline

Start: 2021-09-01
Primary completion: 2022-03-01
Completion: 2022-05-25

Publications

Yamagata T, Ogiwara I, Tatsukawa T, Suzuki T, Otsuka Y, Imaeda N, Mazaki E, Inoue I, Tokonami N, Hibi Y, Itohara S, Yamakawa K. Scn1a-GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neurons. Elife. 2023 May 23;12:e87495. doi: 10.7554/eLife.87495.
Chen Y, Zou H, Hou X, Lan C, Wang J, Qing Y, Chen W, Yao S, Kendrick KM. Oxytocin administration enhances pleasantness and neural responses to gentle stroking but not moderate pressure social touch by increasing peripheral concentrations. Elife. 2023 May 12;12:e85847. doi: 10.7554/eLife.85847.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxytocin	Peptide	24 iu	Intranasal

Indications

No indication recorded.