Efficacy of Chinese Herbal Medicine to Prevent and Treat COVID-19 Close Contacts

Completed 2163 enrolled Hong Kong Baptist University

RandomizedParallel-groupOpen-labelPrevention

Summary

This is a randomized, blank-controlled study in adults with household contact exposure to individuals with SARS-CoV-2 infection. All subjects in the study will be household contacts with close exposure to the first household member known to be newly infected with SARS-CoV-2. Subjects in each cohort will be randomly assigned to the Chinese herbal medicine treatment group or blank control group in a 4:1 ratio, followed by 1 week of the treatment period and 2 weeks of follow-up.

Timeline

Start: 2022-03-14
Primary completion: 2022-06-22
Completion: 2022-06-22

Publications

Du P, Lam WC, Leung C, Li H, Lyu Z, Yuen CS, Cheung CH, Lam TF, Bian Z, Zhong L. Efficacy and safety of Chinese herbal medicine to prevent and treat COVID-19 household close contacts in Hong Kong: an open-label, randomized controlled trial. Front Immunol. 2024 May 10;15:1359331. doi: 10.3389/fimmu.2024.1359331. eCollection 2024.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chinese herbal medicine	Traditional medicine (herbal / TCM)	9 g	Oral

Indications

No indication recorded.