drugset / Trial / NCT05269615
Exercise-induced Erythropoiesis: the Mechanistic of Angiotensin II
RandomizedCrossoverDouble-blindBasic science
Summary
The major aims are to determine the effect of acute (single dose) blockade of ANGII receptor 1 (AT1) on the EPO response to a single session of endurance exercise, as well as determine the effect of chronic (8-week) blockade of AT1 on ET-induced adaptations in total circulating red blood volume and hemoglobin.
Timeline
- Start
- 2023-03-20
- Primary completion
- 2024-09-30
- Completion
- 2024-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Valsartan | Small molecule | 80 mg | — |
Indications
No indication recorded.