drugset / Trial / NCT05273996

Predictors of Cognitive Outcomes in Geriatric Depression

NCT05273996

Phase 4 Active not recruiting 75 enrolled David Steffens National Institute of Mental Health (NIMH) · collab
NaSingle-groupOpen-labelOther

Summary

This study will focus on examining effects of stress on long-term mood and cognitive outcomes of late-life depression. It will also example the neural underpinnings of these changes using structural and functional brain imaging. Understanding how effects of stress in older depressed adults, as well as factors that might minimize those effects, lead to particular mood and cognitive outcomes will inform future development of novel prevention strategies.

Timeline

Start
2021-09-28
Primary completion
2027-04-30
Completion
2027-04-30

Drugs

EvaluationDrugModalityDoseRoute
Background Bupropion Small molecule
Background Desvenlafaxine Other / unclassified
Background Sertraline Small molecule