drugset / Trial / NCT05273996
Predictors of Cognitive Outcomes in Geriatric Depression
Phase 4
Active not recruiting
75 enrolled
David Steffens
National Institute of Mental Health (NIMH) · collab
NaSingle-groupOpen-labelOther
Summary
This study will focus on examining effects of stress on long-term mood and cognitive outcomes of late-life depression. It will also example the neural underpinnings of these changes using structural and functional brain imaging. Understanding how effects of stress in older depressed adults, as well as factors that might minimize those effects, lead to particular mood and cognitive outcomes will inform future development of novel prevention strategies.
Timeline
- Start
- 2021-09-28
- Primary completion
- 2027-04-30
- Completion
- 2027-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Bupropion | Small molecule | — | — |
| Background | Desvenlafaxine | Other / unclassified | — | — |
| Background | Sertraline | Small molecule | — | — |