drugset / Trial / NCT05276063

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

NCT05276063

Phase 2/3 Active not recruiting 90 enrolled Sling Therapeutics, Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twice daily (BID) vs. placebo, at 24 weeks in the treatment of subjects with active, moderate to severe thyroid eye disease (TED).

Timeline

Start
2022-07-01
Primary completion
2024-10-15
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator linsitinib Small molecule Oral