drugset / Trial / NCT05276206

Application of Transversus Abdominus Plain Block, Local Subcutaneous Injection and IV Nalbuphine

NCT05276206

Phase 1 Completed 400 enrolled Egymedicalpedia
RandomizedFactorialQuadruple-blindTreatment

Summary

Approximately 1 in 5 women who undergo CS will experience severe acute postoperative pain. The severity of pain in the acute postoperative period is a significant predictor for the development of chronic pain, which occurs in 9.2%-18% of women who undergo CS. Furthermore, severe acute post-cesarean pain triples a woman's risk of developing postpartum depression and negatively affects breastfeeding and infant care. For these reasons, it is imperative to provide adequate postoperative analgesia in this patient population

Timeline

Start
2022-03-07
Primary completion
2022-03-20
Completion
2022-04-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nalbuphine Small molecule Intravenous

Indications

No indication recorded.