drugset / Trial / NCT05277454

Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT

NCT05277454 ↗

Phase 1 Unknown 113 enrolled Hutchison Medipharma Limited
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the safety and tolerability of HMPL-653 in patients with advanced solid tumors who have failure of standard of care or can not tolerate standard of care or those with TGCT, and to determine the maximum tolerated dose (MTD) and/or the recommended phase II clinical study dose (RP2D) of HMPL-653 in patients with advanced solid tumors.

Timeline

Start
2022-01-18
Primary completion
2024-06-28
Completion
2025-04-14

Drugs

EvaluationDrugModalityDoseRoute
Subject HMPL-653 Unknown — Oral