drugset / Trial / NCT05277623

Effect of Mannitol on Postreperfusion Syndrome During Living Donor Liver Transplant

NCT05277623

Phase 0 Completed 60 enrolled Ain Shams University
RandomizedParallel-groupDouble-blindPrevention

Summary

Postreperfusion syndrome during living liver transplants remains a serious concern for transplant anesthesiologists. This syndrome is responsible for decreases in systemic blood pressure, systemic vascular resistance, and cardiac output and can even lead to cardiac arrest. Delayed graft function and primary graft nonfunction are closely related to postreperfusion syndrome (Therefore, attenuating the syndrome during anesthesia is of great importance.

Timeline

Start
2022-04-04
Primary completion
2022-11-05
Completion
2022-12-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Mannitol Diagnostic / imaging agent 1 g/kg

Indications