drugset / Trial / NCT05284643

Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma

NCT05284643

Recruiting 96 enrolled University of Miami
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this research is to find hidden cancer with an experimental magnetic resonance imaging (MRI) scan called spectroscopic magnetic resonance imaging (sMRI). That spectroscopic MRI scan will be used to increase the area of the brain receiving radiation and then the dose of radiation in attempt to kill more of the cancer. Proton radiotherapy and bevacizumab (Avastin) are used to minimize the possible side effects of this approach.

Timeline

Start
2022-09-30
Primary completion
2027-09-30
Completion
2029-09-30

Drugs

EvaluationDrugModalityDoseRoute
Background Bevacizumab Monoclonal antibody 10 mg/kg Intravenous

Indications