Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms

Summary

This is a open-label, single center to determine the efficacy and safety of IM96 CAR-T cells in Patients With Advanced Digestive System Neoplasms

Timeline

Start

2022-03-10

Primary completion

2024-04-30

Completion

2024-06-30

Publications

• Qi C, Liu C, Gong J, Wang X, Wang Z, Xu T, Liu D, Zhang P, Li J, Zhang M, Zhang X, Lu M, Zhou J, Lu Z, Peng Z, Cao Y, Yuan J, Wang Y, Lu X, He T, Ding Y, Wu F, Liu D, Li J, Shen L. Guanylyl Cyclase 2C-Targeted Chimeric Antigen Receptor T-Cell Therapy in Patients With Metastatic Colorectal Cancer. J Clin Oncol. 2026 Jul 20;44(21):2006-2016. doi: 10.1200/JCO-25-01090. Epub 2026 Jun 4.

Drugs

Indications