ZR-CHOP in DLBCL With Specific Gene Abnormality

Summary

This is a phase 2, single center clinical trial. to evaluating the efficacy and safety of Zanubrutinib in combination with R-CHOP in newly diagnosed diffuse large B-cell lymphoma with specific gene abnormality.

Timeline

Start

2022-01-04

Primary completion

2024-01-04

Completion

2026-01-04

Publications

• Zhang Q, Jiang S, Wei R, Zhang W, Bao L, Liu Y, Jin J, Lv F, Liu C, Liu X, Sun H, Wang J, Tao R, Zhou X, Cao J. Zanubrutinib combined with R-CHOP in previously untreated diffuse large B-cell lymphoma with specific gene alteration: a phase II study. Blood Cancer J. 2026 Jul 1. doi: 10.1038/s41408-026-01553-4. Online ahead of print.

Drugs

Indications