drugset / Trial / NCT05290597

A Phase 1, Open-label, Multicenter, Dose Escalation Study of IBI363 (PD1-IL2m) in Subjects With Advanced Solid Malignancies or Lymphomas

NCT05290597

NaSingle-groupOpen-labelTreatment

Summary

This is a Phase 1, open-label, multicenter, dose-escalation study designed to evaluate the safety, tolerability, and DLTs to establish the maximum tolerated dose (MTD) or maximum administered dose (MAD), and the RP2D of sequential doses of IBI363 (study drug) in subjects with advanced, refractory solid malignancies or lymphomas.

Timeline

Start
2022-08-22
Primary completion
2026-01-28
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject IBI363 Protein / enzyme biologic

Indications