drugset / Trial / NCT05291676
Systems Investigation of Vaccine Responses in Aging and Frailty
Phase 2
Recruiting
96 enrolled
Yale University
National Institute of Allergy and Infectious Diseases (NIAID) · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
This study will compare the immune response signatures (including immunologic, transcriptomic and metabolomic) of the two influenza vaccines approved for use in adults age 65 and over (Fluad and Fluzone High-Dose).
Timeline
- Start
- 2023-11-06
- Primary completion
- 2027-04
- Completion
- 2027-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluad | Vaccine | 0.5 ml | Intramuscular |
| Subject | Fluzone | Vaccine | 0.7 ml | Intramuscular |