drugset / Trial / NCT05294341
Metabolism of 0.35mg Norethindrone vs 5mg Norethindrone Acetate
Non-randomizedCrossoverOpen-labelOther
Summary
0.35mg norethindrone, also known as progesterone only pills, are routinely prescribed as immediate postpartum oral contraception. Norethindrone acetate is prescribed for gynecologic indications, but has never been studied as an efficacious form of contraception. This is a pilot crossover study examining the pharmacokinetics of norethindrone, the metabolically active component of both drugs, in participants taking 5mg norethindrone and 0.35mg norethindrone acetate.
Timeline
- Start
- 2022-07-22
- Primary completion
- 2023-05-01
- Completion
- 2023-05-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Norethindrone | Unknown | 0.35 mg | Oral |
| Comparator | Norethindrone | Unknown | 5 mg | Oral |
Indications
No indication recorded.