drugset / Trial / NCT05294666

Evaluation of 0.05% CsA and 0.1% FK506 Eye Drops in Ocular GVHD Treatment

NCT05294666

Phase 4 Completed 89 enrolled Peking University Third Hospital
Non-randomizedParallel-groupOpen-labelTreatment

Summary

It is planned to explore the efficacy and safety of local 0.05% cyclosporine eye drops in the treatment of chronic graft-versus-host eye disease. Through the comparative study with 0.1% tacrolimus eye drops, to clarify the short-term and long-term efficacy of 0.05% CSA in these patients, and to explore the benefits of long-term maintenance of local cyclosporine to patients.

Timeline

Start
2020-04-01
Primary completion
2021-06-01
Completion
2021-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclosporine Peptide 0.05 % Other
Subject Tacrolimus Small molecule 0.05 % Other