drugset / Trial / NCT05309135
A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to assess the safety of a fixed dose of human corneal endothelial cells when administered with varying concentrations of Rho kinase inhibitor (Y-27632) in patients with corneal edema secondary to endothelial dysfunction.
Timeline
- Start
- 2022-03-24
- Primary completion
- 2023-03-09
- Completion
- 2023-03-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | HCEC-1 | Cell therapy | — | — |
| Subject | Y27632 | Small molecule | — | — |