drugset / Trial / NCT05309460
Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial
RandomizedParallel-groupOpen-labelTreatment
Summary
Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.
Timeline
- Start
- 2022-06-20
- Primary completion
- 2024-05-01
- Completion
- 2024-12-01
Publications
- Background Lovgren T, Connealy B, Yao R, Dahlke JD. Postpartum management of hypertension and effect on readmission rates. Am J Obstet Gynecol MFM. 2022 Jan;4(1):100517. doi: 10.1016/j.ajogmf.2021.100517. Epub 2021 Oct 30.
- Background Lovgren T, Connealy B, Yao R, D Dahlke J. Postpartum medical management of hypertension and risk of readmission for hypertensive complications. J Hypertens. 2023 Feb 1;41(2):351-355. doi: 10.1097/HJH.0000000000003340. Epub 2022 Dec 13.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Labetalol | Small molecule | 200 mg | Oral |
| Comparator | Nifedipine | Other / unclassified | 30 mg | — |