drugset / Trial / NCT05310071

A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease

NCT05310071 ↗

Phase 3 Terminated 1027 enrolled Biogen
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary objective of this study is to verify the clinical benefit of monthly doses of aducanumab in slowing cognitive and functional impairment as measured by changes in the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) score as compared with placebo in participants with early Alzheimer's disease.

Timeline

Start
2022-06-02
Primary completion
2024-08-12
Completion
2024-08-12

Outcome

Outcome not reported

Stopped: “Sponsor's Decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject Aducanumab Monoclonal antibody 10 mg/kg Intravenous

Indications