drugset / Trial / NCT05311514
Allogeneic Platelet Lysate Eye Drops for the Treatment of Severe Chronic Ocular Graft-versus-host Disease
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The study evaluates the efficacy and safety of allogeneic platelet lysate eye drops in patients with severe ocular graft versus host disease refractory to conventional systemic and local treatments. The corneal staining, conjunctival hyperemia, tear film break up time,Schirmer test and ocular surface disease index will be evaluated before and after allogeneic platelet lysate treatment. The safety of allogeneic platelet lysate treatment will be also assessed.
Timeline
- Start
- 2021-04-01
- Primary completion
- 2024-11-29
- Completion
- 2024-11-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Platelet Lysate | Unknown | 20 % | Other |
| Subject | Platelet Lysate | Unknown | 50 % | Other |