drugset / Trial / NCT05311566

PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer

NCT05311566 ↗

Phase 2 Unknown 92 enrolled Lei Li
NaSingle-groupOpen-labelTreatment

Summary

This study is a single-center, single-arm, open-phase II clinical study, the main purpose of which is to evaluate the effectiveness and safety of camrelizumab combined with concurrent chemoradiotherapy for early and locally advanced cervical cancer, i.e., FIGO 2018 IB2-IIIB cervical cancer. Eligible subjects will be given cisplatin and radiotherapy, for 6-8 weeks, camrelizumab repeated every 14 days until disease progression, toxicity intolerance, or other reasons specified in the protocol. Subjects who finished treatment entered the safety follow-up or survival follow-up.

Timeline

Start
2022-03-27
Primary completion
2023-03-27
Completion
2026-03-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Background Cisplatin Other / unclassified 40 mg/m2 Intravenous

Indications