drugset / Trial / NCT05311709
Sotorasib in Advanced KRASG12C-mutated Non-small Cell Lung Cancer Patients With Comorbidities
Phase 2
Unknown
100 enrolled
Vestre Viken Hospital Trust
Aarhus University Hospital · collabHaukeland University Hospital · collabKarolinska University Hospital · collabOdense University Hospital · collabOslo University Hospital · collabRigshospitalet, Denmark · collabSt. Olavs Hospital · collabUniversity Hospital of North Norway · collab
NaSingle-groupOpen-labelTreatment
Summary
A single-arm, multicentre trial to investigate sotorasib in KRASG12C-mutated non-small cell lung cancer stage III/IV not amenable for curative treatment including patients with comorbidities, and to provide translational knowledge regarding mechanism of relapse and differences in responses, including differences among patients with different co-occurring mutations.
Timeline
- Start
- 2022-05-30
- Primary completion
- 2024-10-01
- Completion
- 2025-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sotorasib | Small molecule | — | — |