drugset / Trial / NCT05312021

Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction

NCT05312021 ↗

RandomizedParallel-groupDouble-blindTreatment

Summary

This study is to evaluate whether 16 weeks of treatment with IMR-687 is a safe and effective treatment for patients with Heart Failure with Preserved Ejection Fraction (HFpEF). The primary objective is to evaluate whether IMR-687 reduces NT-proBNP compared to placebo in these patients.

Timeline

Start
2022-04
Primary completion
2023-09
Completion
2023-11

Outcome

Outcome not reported

Stopped: “Study Termination”

Drugs

EvaluationDrugModalityDoseRoute
Subject Tovinontrine Small molecule 300 mg Oral
Subject Tovinontrine Small molecule 400 mg Oral