drugset / Trial / NCT05312021
Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction
RandomizedParallel-groupDouble-blindTreatment
Summary
This study is to evaluate whether 16 weeks of treatment with IMR-687 is a safe and effective treatment for patients with Heart Failure with Preserved Ejection Fraction (HFpEF). The primary objective is to evaluate whether IMR-687 reduces NT-proBNP compared to placebo in these patients.
Timeline
- Start
- 2022-04
- Primary completion
- 2023-09
- Completion
- 2023-11
Outcome
Outcome not reported
Stopped: “Study Termination”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tovinontrine | Small molecule | 300 mg | Oral |
| Subject | Tovinontrine | Small molecule | 400 mg | Oral |