drugset / Trial / NCT05312476

Clinical Study on CAR-T Targeting Igβ Targets in Refractory Relapsed Non-Hodgkin's Lymphoma

NCT05312476 ↗

NaSingle-groupOpen-labelTreatment

Summary

Aim of this study will evaluate the safety, tolerability and preliminary efficacy of chimeric antigen receptor T cells (CAR-T) targeting Igβ targets in patients with Igβ-positive refractory relapsed non-Hodgkin's lymphoma.

Timeline

Start
2026-05-26
Primary completion
2026-05-28
Completion
2026-05-28

Outcome

Outcome not reported

Stopped: “The study did not initiate because manufacturing of the CAR-T product failed.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Chimeric Antigen Receptor T Cells (CAR-T) Targeting Igβ Targets Cell therapy 1e+06 cells/kg —
Subject Chimeric Antigen Receptor T Cells (CAR-T) Targeting Igβ Targets Cell therapy 3e+06 cells/kg —
Subject Chimeric Antigen Receptor T Cells (CAR-T) Targeting Igβ Targets Cell therapy 6e+06 cells/kg —