drugset / Trial / NCT05312710

Safety and Efficacy of APG-157 in Head and Neck Cancer

NCT05312710 ↗

Phase 2 Active not recruiting 24 enrolled Aveta Biomics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this clinical research study is to study safety and efficacy of orally administered APG-157 as the neoadjuvant/induction therapy in newly diagnosed, locally advanced patients with Head \& Neck Cancer of oral cavity and/or oropharynx. The study hypothesis is that neoadjuvant use of APG-157 will reduce the tumor burden prior to any definitive therapy to improve the outcomes over current standard of care.

Timeline

Start
2022-04-22
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject APG-157 Unknown 100 mg Oral