drugset / Trial / NCT05312840

Efficacy and Safety of Conventional and Low-dose Platinum Gemcitabine Combined With Sintilimab With Delayed Administration in First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer

NCT05312840

Phase 4 Completed 20 enrolled People's Hospital of Quzhou
RandomizedParallel-groupOpen-labelTreatment

Summary

To observe the efficacy and safety of conventional and low-dose platinum Gemcitabine combined with Sintilimab with delayed administration in first-line treatment of advanced squamous non-small cell lung cancer.

Timeline

Start
2022-01-01
Primary completion
2024-12-31
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 3 unknown Intravenous
Subject Carboplatin Small molecule 5 unknown Intravenous
Subject Cisplatin Other / unclassified 56 mg/m2 Intravenous
Subject Cisplatin Other / unclassified 75 mg/m2 Intravenous
Subject Gemcitabine Small molecule 750 mg/m2 Intravenous
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Sintilimab Monoclonal antibody 200 mg Intravenous