Erythropoietin Therapy to Induce Regulatory T Cells in Liver Transplant Recipients

Summary

The hypothesis of this proof-of-concept study is that EPO increases the frequency, stability and/or function of Tregs in liver transplant recipients. We also hypothesize that EPO will have a greater effect in everolimus vs. tacrolimus treated LTR, thus providing the rationale for a subsequent clinical trial to utilize EPO in combination with everolimus as a more successful pathway toward tolerance.

Timeline

Start

2022-02-18

Primary completion

2023-05-23

Completion

2024-09-30

Drugs

Indications