MAGnesium Effect With ANtiosteoporotic Drugs

Summary

Randomized pilot clinical trial to demonstrate superiority of bisphosphonate-magnesium combination over bisphosphonates alone in postmenopausal osteoporosis in slowing bone remodeling as assessed by C-terminal telopeptide of bone collagen type 1 (CTX) dosage.

Timeline

Start

2022-06-28

Primary completion

2024-12-19

Completion

2024-12-19

Publications

• Pickering ME, Morel V, Nicolas M, Duale C, Sortais E, Graven-Nielsen T, Pereira B, Pickering G. Quantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation. Aging Clin Exp Res. 2026 Jan 21;38(1):67. doi: 10.1007/s40520-025-03317-9.

Drugs

Indications