drugset / Trial / NCT05329623

A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.

NCT05329623

Phase 1 Completed 33 enrolled Novartis Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the effect of hepatic impairment on the systemic pharmacokinetics (PK), safety, and tolerability of JDQ443 in participants with varying degrees of hepatic impairment.

Timeline

Start
2022-05-03
Primary completion
2024-04-07
Completion
2024-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Opnurasib Small molecule 200 mg Oral