drugset / Trial / NCT05334017
Xylometazoline and Cocaine for Nasal Vasoconstriction
RandomizedParallel-groupTriple-blindPrevention
Summary
The objective of this study is to compare xylometazoline and cocaine's effect on minimizing epistaxis when administered as a local vasoconstrictor prior to nasal intubation. The investigators hypothesize that there will be a lower bleeding score in the group receiving xylometazoline as compared with the group receiving cocaine.
Timeline
- Start
- 2022-09-08
- Primary completion
- 2023-03-21
- Completion
- 2023-03-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cocaine | Small molecule | 2 ml | Intranasal |
| Comparator | Cocaine | Small molecule | 4 % | Intranasal |
| Comparator | Xylometazoline | Small molecule | 0.1 % | Intranasal |
| Comparator | Xylometazoline | Small molecule | 1 ml | Intranasal |
Indications
No indication recorded.