drugset / Trial / NCT05335005

MK-2060 and Clopidogrel Co-administration Safety and Tolerability Study in Participants With End-Stage Renal Disease (ESRD) (MK-2060-008)

NCT05335005 ↗

Phase 1 Completed 12 enrolled Merck Sharp & Dohme LLC
NaSingle-groupOpen-labelTreatment

Summary

MK-2060 is being developed for prevention of thrombotic complications in end-stage renal disease (ESRD). The purpose of this study is to conduct a preliminary evaluation of the safety and tolerability of MK-2060 treatment in combination with a commonly used P2Y12 receptor inhibitor, clopidogrel, in ESRD patients.

Timeline

Start
2022-05-30
Primary completion
2023-02-14
Completion
2023-02-14

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-2060 Monoclonal antibody 25 mg Intravenous