drugset / Trial / NCT05338658

Study of PAT in Patients With Solid Tumor Cancers

NCT05338658 ↗

Phase 1 Recruiting 21 enrolled Masonic Cancer Center, University of Minnesota
NaSingle-groupOpen-labelTreatment

Summary

This is a single center Phase I study with extension of peptide alarm therapy (PAT) administered by intratumoral (IT) injection during the 1st course of a standard of care intravenous PD-1/PD-L1 inhibitor for the treatment of locally advanced or metastatic solid tumor cancers that has failed to be controlled after one or more prior therapies including a previous PD-1/PD-L1 inhibitor

Timeline

Start
2023-05-19
Primary completion
2027-01
Completion
2027-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Peptide Alarm Therapy Unknown — Other
Background Pembrolizumab Monoclonal antibody 200 mg Intravenous