drugset / Trial / NCT05338658
Study of PAT in Patients With Solid Tumor Cancers
NaSingle-groupOpen-labelTreatment
Summary
This is a single center Phase I study with extension of peptide alarm therapy (PAT) administered by intratumoral (IT) injection during the 1st course of a standard of care intravenous PD-1/PD-L1 inhibitor for the treatment of locally advanced or metastatic solid tumor cancers that has failed to be controlled after one or more prior therapies including a previous PD-1/PD-L1 inhibitor
Timeline
- Start
- 2023-05-19
- Primary completion
- 2027-01
- Completion
- 2027-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Peptide Alarm Therapy | Unknown | — | Other |
| Background | Pembrolizumab | Monoclonal antibody | 200 mg | Intravenous |