Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Subjects (Food Effect Study)

Summary

To evaluate the effect of food on the pharmacokinetics of oral edaravone in healthy adult subjects. In this study, we determined 5 different dietary conditions including 4 different meal contents and fasting condition.

Timeline

Start

2019-06-10

Primary completion

2019-07-24

Completion

2019-07-24

Publications

• Results Shimizu H, Nishimura Y, Shiide Y, Akimoto M, Matsuda H, Kato Y, Hirai M. Food Effect Study to Assess the Impact on Edaravone Pharmacokinetic Profiles in Healthy Participants. Clin Ther. 2022 Dec;44(12):1552-1565. doi: 10.1016/j.clinthera.2022.10.001. Epub 2022 Nov 12.

Drugs

Indications

No indication recorded.