Utidelone Plus Bevacizumab for Advanced Breast Cancer With Brain Metastases

Summary

This study aims to investigate the efficacy and safety of utidelone in combination with bevacizumab in the treatment of advanced breast cancer with brain metastases, and thus provides a new systemic treatment strategy for those patients.

Timeline

Start

2022-04-29

Primary completion

2024-05

Completion

2024-05

Publications

• Yan M, Lv H, Liu X, Wang S, Geng C, Song Y, Liu Z, Niu L, Zhang M, Wang C, Feng Y, Zeng H, Sun H, Wang J, Xiang Y, Tang L, Qiu R. Utidelone Plus Bevacizumab for ERBB2-Negative Metastatic Breast Cancer and Active Brain Metastases: The U-BOMB Phase 2 Nonrandomized Clinical Trial. JAMA Oncol. 2025 Aug 1;11(8):883-889. doi: 10.1001/jamaoncol.2025.1694.

Drugs

Indications