drugset / Trial / NCT05358379

A Study to Investigate CYC140, in Subjects With Advanced Solid Tumors and Lymphoma

NCT05358379 ↗

Phase 1/2 Unknown 330 enrolled Cyclacel Pharmaceuticals, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a 2-part, phase 1/2, open-label, multicenter study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, pharmacogenomics, and efficacy of CYC140 administered orally daily. This study consists of Phase 1 and Phase 2 components in subjects with advanced solid tumors and lymphoma who have progressed despite having standard therapy or for which no standard therapy exists.

Timeline

Start
2022-04-14
Primary completion
2025-08
Completion
2025-11

Drugs

EvaluationDrugModalityDoseRoute
Subject CYC140 Unknown 5 mg Oral

Indications