drugset / Trial / NCT05360368

HLX07(Anti-EGFR mAb) in Patients With Advanced or Metastatic Solid Tumors

NCT05360368

Phase 1 Unknown 24 enrolled Shanghai Henlius Biotech
NaSingle-groupOpen-labelTreatment

Summary

This Phase1, open-label and dose-escalation study will evaluate the safety, tolerability, pharmacokinetics, and preliminary anti-tumor efficacy of HLX07 administered as a single-agent by IV infusion every 3 weeks to patients with locally advanced or metastatic solid malignancies, who have failed or are intolerant to standard therapy, or for whom no standard therapy is available.

Timeline

Start
2023-03-30
Primary completion
2023-12-30
Completion
2024-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject PIMURUTAMAB Monoclonal antibody 800 mg Intravenous
Subject PIMURUTAMAB Monoclonal antibody 1200 mg Intravenous
Subject PIMURUTAMAB Monoclonal antibody 1500 mg Intravenous
Subject PIMURUTAMAB Monoclonal antibody 1800 mg Intravenous

Indications