drugset / Trial / NCT05360368
HLX07(Anti-EGFR mAb) in Patients With Advanced or Metastatic Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
This Phase1, open-label and dose-escalation study will evaluate the safety, tolerability, pharmacokinetics, and preliminary anti-tumor efficacy of HLX07 administered as a single-agent by IV infusion every 3 weeks to patients with locally advanced or metastatic solid malignancies, who have failed or are intolerant to standard therapy, or for whom no standard therapy is available.
Timeline
- Start
- 2023-03-30
- Primary completion
- 2023-12-30
- Completion
- 2024-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PIMURUTAMAB | Monoclonal antibody | 800 mg | Intravenous |
| Subject | PIMURUTAMAB | Monoclonal antibody | 1200 mg | Intravenous |
| Subject | PIMURUTAMAB | Monoclonal antibody | 1500 mg | Intravenous |
| Subject | PIMURUTAMAB | Monoclonal antibody | 1800 mg | Intravenous |