drugset / Trial / NCT05363527
Aging and Reward System Response to Inflammation and Anxiety Study
Phase 1
Completed
40 enrolled
University of California, Los Angeles
National Institute on Aging (NIA) · collab
RandomizedParallel-groupQuadruple-blindOther
Summary
The purpose of this study is to use an experimental inflammatory challenge to examine whether older adults with symptoms of anxiety experience loss of pleasure or loss of motivation when they are exposed to inflammation. Loss of pleasure or loss of motivation will be evaluated using self-report questionnaires, computer tasks, and during a brain scan.
Timeline
- Start
- 2023-03-29
- Primary completion
- 2025-12-08
- Completion
- 2025-12-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lipopolysaccharide | Other / unclassified | 0.8 ng | Intravenous |