drugset / Trial / NCT05366179
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to test the safety of using T lymphocyte chimeric antigen receptor cells against the B7-H3 antigen (CAR.B7-H3T cells) in patients with glioblastoma. CAR.B7-H3T cells treatment has not been tested in humans and is not an approved treatment by the Food and Drug Administration for glioblastoma.
Timeline
- Start
- 2022-09-02
- Primary completion
- 2030-05-30
- Completion
- 2030-05-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CAR.B7-H3T cells | Cell therapy | 2e+06 cells | Intravitreal |
| Subject | CAR.B7-H3T cells | Cell therapy | 5e+06 cells | Intravitreal |