drugset / Trial / NCT05369884
Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D
Phase 0
Unknown
216 enrolled
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine · collabThe First Affiliated Hospital of Henan University of Traditional Chinese Medicine · collabThe First Affiliated Hospital of Shanxi University of Traditional Chinese Medicine · collabTianjin Nankai Hospital · collabYunnan Provinical Hospital of Traditional Chinese Medicine · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Non-erosive reflux disease（NERD）and Diarrhea-Predominant Irritable Bowel Syndrome（IBS-D）are both the common refractory gastrointestinal diseases. Patients, who suffered from overlapping symptoms of NERD and IBS-D, present more serious symptom manifestation, anxiety, and worse life quality than those with solely disease. There is lack of effective treatment for overlapping gastrointestinal symptoms. Traditional Chinese Medicine (TCM) syndrome differentiation and treatment has the advantages of overall regulation and individualized treatment, but lack of high-level evidence. The purpose of this study is to evaluate the efficacy and safety of WPQW granule for the treatment of NERD overlapping IBS-D.
Timeline
- Start
- 2021-12-01
- Primary completion
- 2023-05
- Completion
- 2023-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | WPQW granule | Unknown | 2 unknown | Oral |