drugset / Trial / NCT05374603

Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC

NCT05374603

Phase 2 Active not recruiting 47 enrolled AstraZeneca
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, interventional, multiple-center, exploratory Phase II study sponsored by AstraZeneca Investment(China)Co., LTD. to evaluate the efficacy and safety of Savolitinib combine with Durvalumab in Chinese EGFR wild-type locally advanced or metastatic NSCLC patients with MET alteration.

Timeline

Start
2022-11-15
Primary completion
2027-01-18
Completion
2027-01-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg Intravenous
Subject Savolitinib Small molecule 400 mg Oral
Subject Savolitinib Small molecule 600 mg Oral

Indications