drugset / Trial / NCT05375916

Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries

NCT05375916

Completed 80 enrolled University of Alberta
RandomizedParallel-groupSingle-blindTreatment

Summary

The advantage of slow-release opioid allows for less fluctuation in drug (pain killer) levels in the blood and an extended period within the effective range for pain relief. The slow-release opioids have been preferred over the short-acting opioids because of the longer duration of action, which lessens the frequency and severity of end-of-dose pain. Herein, the investigators propose the use of low dose slow-release opioid formulation offers better pain control in the first 48 hours post-operatively in open abdominal urologic surgeries.

Timeline

Start
2022-05-03
Primary completion
2023-11-30
Completion
2023-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydromorphone Other / unclassified 1 mg
Subject Hydromorphone Other / unclassified 3 mg
Subject Hydromorphone Other / unclassified 4 mg