drugset / Trial / NCT05375916
Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries
RandomizedParallel-groupSingle-blindTreatment
Summary
The advantage of slow-release opioid allows for less fluctuation in drug (pain killer) levels in the blood and an extended period within the effective range for pain relief. The slow-release opioids have been preferred over the short-acting opioids because of the longer duration of action, which lessens the frequency and severity of end-of-dose pain. Herein, the investigators propose the use of low dose slow-release opioid formulation offers better pain control in the first 48 hours post-operatively in open abdominal urologic surgeries.
Timeline
- Start
- 2022-05-03
- Primary completion
- 2023-11-30
- Completion
- 2023-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydromorphone | Other / unclassified | 1 mg | — |
| Subject | Hydromorphone | Other / unclassified | 3 mg | — |
| Subject | Hydromorphone | Other / unclassified | 4 mg | — |