drugset / Trial / NCT05377619
Preventing Gastric Glitch With Prucalopride and Buspirone: N-of-1 Clinical Trial
RandomizedSequentialDouble-blindPrevention
Summary
Background: Gastric glitch is a new functional disease characterized by severe and transient epigastric pain occurring after challenges such as drinking alcohol and eating specific foods. Aims: In this N-of-1 trial, we first characterized the clinical and gastric tomographic images of a patient with gastric glitch highly reproducible after alcohol challenging, and then tested the effect of prucalopride and buspirone on the prevention of gastric glitch crises.
Timeline
- Start
- 2022-01-06
- Primary completion
- 2022-03-06
- Completion
- 2022-03-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Buspirone | Small molecule | 10 mg | Oral |
| Subject | Prucalopride | Small molecule | 2 mg | Oral |