drugset / Trial / NCT05384249

Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis

NCT05384249

Phase 2 Terminated 96 enrolled ACELYRIN Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin-17A, to which it binds with high affinity. This study investigates izokibep in subjects with active non-infectious, intermediate-, posterior- or pan-uveitis requiring high-dose steroids.

Timeline

Start
2022-08-23
Primary completion
2025-02-07
Completion
2025-02-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Izokibep Protein / enzyme biologic Subcutaneous

Indications