drugset
drugset / Trial / NCT05384678

Acute Dose-dependent Effects of DMT in Healthy Subjects

NCT05384678 ↗

Phase 1 Completed 24 enrolled University Hospital, Basel, Switzerland
RandomizedCrossoverTriple-blindBasic science

Summary

N,N-dimethyltryptamine (DMT) is a psychoactive substance with similar effects such as LSD or psilocybin. However, DMT is less well characterized than the latter substances. The present study is a modern randomized cross-over trial, investigating different continuous intravenous DMT dose rates over a broad dose range. Thus, different doses will be tested and related to subjective and autonomic effects.

Timeline

Start
2022-11-15
Primary completion
2024-03-08
Completion
2024-03-13

Drugs

EvaluationDrugModalityDoseRoute
Subject N,N-Dimethyltryptamine Unknown 54 mg Intravenous
Subject N,N-Dimethyltryptamine Unknown 108 mg Intravenous
Subject N,N-Dimethyltryptamine Unknown 162 mg Intravenous
Subject N,N-Dimethyltryptamine Unknown 216 mg Intravenous

Indications

No indication recorded.