drugset / Trial / NCT05387239

Safety and Effectiveness of VL-PX10 + VL-P22 Treatment on Pulmonary Fibrosis Secondary to Covid-19

NCT05387239 ↗

Phase 2 Suspended 20 enrolled Vitti Labs, LLC
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The COVID-induced fibrotic lung damage continues long after viral infection has subsided and is exhibited by severe respiratory pathology and concomitant symptoms. The long-lasting sequelae in patients who have recovered from severe COVID indicate that there is a 30% chance of developing a persistent respiratory system pathology and a 10% chance of developing a severe pathology. The symptoms of lung fibrosis include a severe disruption of respiration, reduction of exercise tolerance, and concomitant development of persistent fibrotic lung damage. This study intends to evaluate benefits of a combination of VL-P22 and VL-PX10 in Covid-19 patients exhibiting pulmonary fibrosis.

Timeline

Start
2022-11-30
Primary completion
2024-11
Completion
2024-12

Outcome

Outcome not reported

Stopped: “Sponsor request”

Drugs

EvaluationDrugModalityDoseRoute
Subject VL-P22 Unknown — Intravenous
Subject VL-PX10 Other / unclassified — Intravenous