drugset / Trial / NCT05389930

Cannabis' Impact on Alcohol Consumption

NCT05389930

RandomizedFactorialDouble-blindBasic science

Summary

This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.

Timeline

Start
2023-03-16
Primary completion
2027-03-31
Completion
2027-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Alcohol Other / unclassified 0.3 g/kg Oral
Subject CBD-dominant cannabis Unknown 367 mg Inhaled
Subject THC-dominant cannabis Unknown 367 mg Inhaled