drugset / Trial / NCT05391490

Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies

NCT05391490 ↗

Phase 1 Not yet recruiting 12 enrolled University College, London
NaSingle-groupOpen-labelTreatment

Summary

KCAT19 is a single-centre, non-randomised, open-label Phase I clinical trial of an Advanced Therapy Investigational Medicinal Product (ATIMP) in adults (age 16-65 years) with high risk, relapsed/refractory (r/r) B cell malignancies.

Timeline

Start
2022-10
Primary completion
2024-11
Completion
2034-11

Drugs

EvaluationDrugModalityDoseRoute
Subject KCAT19 T cells Cell therapy — Intravenous