drugset / Trial / NCT05394012

A Phase 1a Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19

NCT05394012

RandomizedParallel-groupDouble-blindPrevention

Summary

This is a phase Ⅰa, randomized, double-blind, positive control trial in healthy adults, intended to evaluate the safety and immunogenicity profile of RQ3013. The study vaccine is administered IM at upper arm deltoid as a two-dose primary series on day 0, 28.

Timeline

Start
2022-12
Primary completion
2023-02
Completion
2023-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator BNT162b2 Messenger RNA (mRNA) 30 ug
Subject RQ3013 Messenger RNA (mRNA) 30 ug Intramuscular
Subject RQ3013 Messenger RNA (mRNA) 60 ug Intramuscular

Indications