drugset / Trial / NCT05397093
ITIL-306 in Advanced Solid Tumors
Non-randomizedParallel-groupOpen-labelTreatment
Summary
ITIL-306-201 is a phase 1a/1b, multicenter, clinical trial evaluating the safety and feasibility of ITIL-306 in adult participants with advanced solid tumors whose disease has progressed after standard therapy. ITIL-306 is a cell therapy derived from a participant's own tumor-infiltrating immune cells (lymphocytes; TILs) and contains a unique molecule designed to increase TIL activity when it encounters folate receptor α (FOLR1) on the tumor.
Timeline
- Start
- 2022-08-24
- Primary completion
- 2023-10-10
- Completion
- 2026-03-06
Outcome
Outcome not reported
Stopped: “The study was terminated early due to discontinuation of development of the investigational program”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ITIL-306 | Cell therapy | — | — |