drugset / Trial / NCT05397093

ITIL-306 in Advanced Solid Tumors

NCT05397093 ↗

Phase 1 Terminated 1 enrolled Instil Bio
Non-randomizedParallel-groupOpen-labelTreatment

Summary

ITIL-306-201 is a phase 1a/1b, multicenter, clinical trial evaluating the safety and feasibility of ITIL-306 in adult participants with advanced solid tumors whose disease has progressed after standard therapy. ITIL-306 is a cell therapy derived from a participant's own tumor-infiltrating immune cells (lymphocytes; TILs) and contains a unique molecule designed to increase TIL activity when it encounters folate receptor α (FOLR1) on the tumor.

Timeline

Start
2022-08-24
Primary completion
2023-10-10
Completion
2026-03-06

Outcome

Outcome not reported

Stopped: “The study was terminated early due to discontinuation of development of the investigational program”

Drugs

EvaluationDrugModalityDoseRoute
Subject ITIL-306 Cell therapy — —